Not so simple Herpes Simplex

Herpes simplex virus (HSV) 1 and 2 are closely related to each other and more distantly related to Varicella Zoster virus (VZV), which causes Varicella (chicken pox) and Herpes Zoster (shingles). Traditionally HSV1 causes most oral herpes and HSV2 causes most genital herpes. But this is no longer so and has changed, probably due to more frequent oral sex.

Figures from Clinipath 2017:

HSV Swab Origin HSV1 HSV2 VZV
Oral sites 93% 2% 5%
Genital/perineal sites 45% 50% 5%

HSV1 is frequently acquired in childhood and 75% of Australian adults would have had HSV1 ...

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