PPIs increase diabetes risk

So first it was enteric infections and bone fractures, now, the latest evidence suggests PPIs increase the risk of developing type 2 diabetes.

Following analysis of data from three large prospective cohorts, Chinese researchers have determined that taking PPIs regularly (and that’s only two or more times a week) confers a 24% higher risk of developing type 2 diabetes than if the acid-suppressing medication isn’t being taken.

And it seems the longer the PPIs are taken, the higher the risk.

“The risk of diabetes was likely to increase with the duration of PPI use and to decrease with the time stopping PPIs, ” the study authors wrote in the journal, Gut.

To study the potential association, researchers investigated almost 210, 000 participants enrolled in one of three ...

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