Preventing Alzheimer Disease

At first read, the study results seemed disappointing. Yet another promising premise fails to deliver when it comes to actual proof.

But the researchers aren’t ready to give up on this hypothesis just yet.

In fact, commentators on the study say the results offer ‘great hope’ and represent ‘a major leap forward.’

The SPRINT MIND study, recently published in JAMA was investigating whether intensive blood pressure control (to a systolic less than 120mmHg) worked better than standard blood pressure control (SBP<140mmHg) at reducing the risk of mild cognitive impairment and dementia.

This randomised controlled trial was a component of the well-publicised Systolic Blood Pressure Intervention Trial (SPRINT) which looked at the effect of more intensive blood pressure control on cardiovascular and renal outcomes in addition to cognitive function in over 9000 people without a history of diabetes or stroke.

Basically, what this study showed was that intensive blood pressure control to ...

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