SSRIs risky after haemorrhagic stroke

And to start the year we have one of those devil or deep blue sea dilemmas.

US researchers have determined that if you give patients who have had a haemorrhagic stroke SSRIs you are more likely to effectively treat their depression. But … those same drugs increase their risk of having another cerebral bleed.

The observational cohort study of almost 1300 survivors of intracerebral haemorrhage showed depression was common – occurring in more than 60% of patients. And yes if these patients were commenced on an SSRI they had a 55% higher chance of resolution of their depressive symptoms – but the downside was that they had a 30% increased risk of recurrence. It’s ...

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